Slow Cooker Mississippi Pot Roast

Featured in: One-Pot Comfort Meals

This slow-cooked beef roast features a tender chuck roast seasoned with ranch and au jus mixes, enhanced by the buttery richness and zing of pepperoncini peppers. The long, gentle cooking process breaks down the meat, creating juicy, flavorful bites perfect for family meals or busy nights. Served best alongside mashed potatoes, rice, or sandwich rolls, this dish offers hearty, comforting flavors with minimal preparation involved. Optional searing boosts depth, while pepper choices can be adjusted to preference.

Updated on Mon, 24 Nov 2025 09:44:00 GMT
Tender Slow Cooker Mississippi Pot Roast, shredded and glistening, ready for serving with creamy sides. Save to Pins
Tender Slow Cooker Mississippi Pot Roast, shredded and glistening, ready for serving with creamy sides. | cocoastone.com

A melt-in-your-mouth, ultra-tender beef roast slow-cooked with ranch, au jus, butter, and tangy pepperoncini. The ultimate comfort food with minimal prep, perfect for busy weeknights or family gatherings.

This recipe quickly became a family favorite after my first try; the tender beef and tangy peppers are unforgettable.

Ingredients

  • Beef: 1 (3–4 lb / 1.4–1.8 kg) chuck roast
  • Seasonings & Sauces: 1 packet (1 oz/28 g) ranch seasoning mix (gluten-free if needed), 1 packet (1 oz/28 g) au jus gravy mix (gluten-free if needed), ½ teaspoon freshly ground black pepper
  • Condiments & Fats: ½ cup (1 stick/115 g) unsalted butter
  • Vegetables: 8–10 whole pepperoncini peppers (plus 2 tbsp brine)

Instructions

Step 1:
Pat the chuck roast dry with paper towels and place it in the bottom of your slow cooker.
Step 2:
Sprinkle the ranch seasoning mix and au jus gravy mix evenly over the roast.
Step 3:
Add the black pepper.
Step 4:
Arrange the pepperoncini peppers around and on top of the beef. Drizzle the brine over the roast.
Step 5:
Place the stick of butter directly on top of the roast.
Step 6:
Cover and cook on LOW for 8 hours, or until the beef is tender and shreds easily with a fork.
Step 7:
Use two forks to shred the beef in the slow cooker, mixing it with the juices and peppers.
Step 8:
Serve hot over mashed potatoes, rice, or on sandwich rolls.
Juicy slow cooker Mississippi Pot Roast, with visible pepperoncini, offering a tangy, savory aroma. Save to Pins
Juicy slow cooker Mississippi Pot Roast, with visible pepperoncini, offering a tangy, savory aroma. | cocoastone.com

This meal often brings everyone to the table early, sharing stories as the rich flavors fill the kitchen.

Notes

Leftovers make excellent sandwiches or sliders. Pair with creamy mashed potatoes and steamed green beans.

Required Tools

6-quart (or larger) slow cooker, forks for shredding, knife and cutting board (optional for trimming beef)

Allergen Information

Contains milk (butter) and may contain gluten (seasoning mixes). To ensure gluten-free, use certified gluten-free ranch and au jus packets. Always check ingredient labels for potential allergens.

Close-up of fork-tender Slow Cooker Mississippi Pot Roast, rich with flavorful juices and butter. Save to Pins
Close-up of fork-tender Slow Cooker Mississippi Pot Roast, rich with flavorful juices and butter. | cocoastone.com

This melt-in-your-mouth roast is not only simple but reliably delicious every time you make it.

Frequently Asked Questions

What cut of beef is best for this dish?

A chuck roast between 3 to 4 pounds works best, as it becomes tender and juicy when slow-cooked over several hours.

Can I prepare this meal ahead of time?

Yes, you can sear the roast and prepare the seasoning before slow cooking. Leftovers also reheat well and make excellent sandwiches.

What is the role of pepperoncini in this dish?

Pepperoncini add a tangy, mildly spicy flavor and moisture, balancing the rich butter and seasoning blends during cooking.

Is it necessary to sear the meat before slow cooking?

Searing is optional but enhances flavor by caramelizing the surface of the roast prior to slow cooking.

What are suitable sides for this beef preparation?

Classic pairings include creamy mashed potatoes, steamed green beans, or soft sandwich rolls to complement the juicy shredded beef.

Slow Cooker Mississippi Pot Roast

Ultra-tender beef cooked with ranch, au jus, butter, and tangy pepperoncini for effortless comfort.

Prep duration
10 minutes
Cooking duration
480 minutes
Overall time
490 minutes
Created by Mara Ellison

Recipe type One-Pot Comfort Meals

Skill level Easy

Cuisine type American

Portion size 6 Portions

Dietary guidelines Reduced-Carb

What You'll Need

Beef

01 1 (3 to 4 lb) chuck roast

Seasonings & Sauces

01 1 packet (1 oz) ranch seasoning mix, gluten-free if required
02 1 packet (1 oz) au jus gravy mix, gluten-free if required
03 ½ teaspoon freshly ground black pepper

Condiments & Fats

01 ½ cup (1 stick) unsalted butter

Vegetables

01 8 to 10 whole pepperoncini peppers with 2 tablespoons brine

Directions

Step 01

Prepare Beef: Pat the chuck roast dry using paper towels and transfer it to the slow cooker base.

Step 02

Add Seasonings: Evenly distribute the ranch seasoning mix and au jus gravy mix over the surface of the beef.

Step 03

Season with Pepper: Sprinkle freshly ground black pepper over the beef and seasonings.

Step 04

Arrange Peppers and Brine: Place whole pepperoncini peppers around and atop the roast; drizzle with 2 tablespoons of pepperoncini brine.

Step 05

Add Butter: Set the entire stick of unsalted butter directly on top of the roast.

Step 06

Slow Cook: Cover the slow cooker and cook on LOW for 8 hours until the beef is tender and easily shred with a fork.

Step 07

Shred Beef: Using two forks, shred the beef within the slow cooker, mixing it thoroughly with the cooking juices and peppers.

Step 08

Serve: Serve the shredded beef hot over mashed potatoes, rice, or sandwich rolls.

Necessary equipment

  • 6-quart or larger slow cooker
  • Two forks for shredding meat
  • Knife and cutting board (optional)

Allergen details

Review the ingredients for allergies and reach out to a healthcare provider if uncertain.
  • Contains milk (butter); seasoning mixes may contain gluten.
  • Use certified gluten-free mixes to ensure gluten-free preparation.
  • Check ingredient labels carefully for allergens.

Nutrition per portion

This nutritional data is intended for reference and doesn't replace professional medical advice.
  • Total calories: 470
  • Total fat: 36 g
  • Carbohydrates: 4 g
  • Proteins: 33 g